Clinical Science of Nutrition
Original Article

Clinical evaluation of the effectiveness of different nutritional support techniques in the intensive care unit

1.

Department of General Surgery, Ankara University School of Medicine, Ankara, Turkey

2.

Department of General Surgery, Gülhane Training and Research Hospital, Ankara, Turkey

3.

Clinical Nutrition Commission, Ankara University School of Medicine, Ankara, Turkey

Clin Sci Nutr 2019; 1: 33-37
DOI: 10.5152/ClinSciNutr.2019.43
Read: 945 Downloads: 382 Published: 20 March 2019

Objective: Malnutrition is a common condition in patients admitted to intensive care units (ICUs). Proper nutritional support is essential to reduce malnutrition-associated morbidity and mortality. The aim of this study was to evaluate the effectiveness of different nutritional support techniques in ICUs on some nutritional and inflammatory biochemical parameters.

Methods: In this retrospective study, 143 patients with a history of admission to ICUs were divided into three groups according to form of nutritional therapy: oral nutritional supplementation (ONS), enteral tube feeding (ETF), and parenteral nutrition (PN). Patients’ demographic characteristics, length of stay in the ICU, length of nutritional support, serum prealbumin levels, C-reactive protein (CRP) levels, and transferrin levels at the time of nutritional supplementation initiation and treatment discontinuation were evaluated.

Results: The change in median serum prealbumin, CRP, and transferrin levels measured on days when nutritional therapy was initiated and terminated was not statistically significant (p=0.537, p=0.635, and p=0.073; respectively) in patients with ONS. Median prealbumin (0.14 vs. 0.21 mg/dL; p<0.001) and transferrin saturation (1.55% vs. 1.87%; p=0.001) levels significantly increased in patients who received ETF. In addition, median CRP (85.5 vs. 30.8 mg/L; p=0.001) levels significantly decreased. In patients with PN, only a significant increase in prealbumin level (0.10 vs. 0.13 mg/dL; p=0.003) was observed. The increases in CRP and transferrin saturation levels were not statistically significant (p=0.730 and p=0.243; respectively).

Conclusion: In the present study, a significant improvement was observed in the prealbumin, CRP, and transferrin levels in patients supported with ETF. However, similar improvement was not observed in patients with ONS.

 

Cite this article as: Çetinkaya ÖA, Çelik SU, Sonyürek Arı P, Demirer S. Clinical evaluation of the effectiveness of different nutritional support techniques in the intensive care unit. Clin Sci Nutr 2019; 1(1): 33-7.

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